Description

Description

Bromazolane (XLI-268) is a triazolobenzodiazepine (TBZD) first synthesized in 1976. It is a bromo analogue of alprazolam rather than a chloro analogue, and has sedative and anxiolytic effects similar to alprazolam and other benzodiazepines. Bromozolam is a non-subtype selective agonist at the benzodiazepine site of the GABA A receptor, with a binding affinity of 2.81 nM for the α 1 subtype and 0.69 nM for the α 2 subtype, with the “common” dose range for bromozolam users reported to be 1 to 2 mg, suggesting that its potency is similar to that of alprazolam.

Chinese name: Dechloroethazole

English name: 8-bromo-1-methyl-6-phenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine

Molecular formula: C17H13BrN4

Molecular weight: 353.21600

Exact mass: 352.03200

PSA: 43.07000

LogP: 3.12480

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